IHORMONI YOKUKHULA, UMHLA WOMNTU: 12629-01-5 HGH

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Ukusetyenziswa kweKlinikhi yokuKhula koMntu iHormone(hGH) yiprotheyini eyimfuneko ekukhuleni okuqhelekileyo kunye nophuhliso ebantwini.IHormone yokuKhula koMntu (hGH) ichaphazela imiba emininzi yophuhliso lomntu kunye nemetabolism kubandakanya ukukhula kobude, ukulawulwa (ukwanda) kweprotein synthesis kunye ne-lipolysis, kunye nommiselo (ukuncipha) kwe-glucose metabolism.IHormone yokuKhula koMntu (hGH) isetyenziswe njengechiza ukusukela ngeminyaka yoo-1950s, kwaye iye yaphumelela kakhulu kunyango lokusilela kwehomoni yokukhula, ukusilela kwezintso okungapheliyo, i-Turner syndrome, ukusilela kwe-lactate kubasetyhini, kunye nePrader-Willisyndrome.Kwimbali yayo ende, ihomoni iphumelele ngokuphawulekayo kwaye ayinayo imiphumo emibi.
Ukusetyenziswa kwezonyango i-GHD iphathwa nge-GH ehlanjululweyo kunye ne-recombinant yabantu.Kungekudala, imiphumo ekubunjweni komzimba, ubunzima bemisipha kunye namandla, amandla okusebenza, i-glucose kunye neprofayili ye-lipid, i-bone metabolism, kunye nomgangatho wobomi kubonakaliswe kwi-GHD yabantu abadala.I-Acromegaly iphathwa nge-somatostatin analogs, i-dopamine antagonists, kunye nabachasi be-GHR.