iphepha_ibhena

iimveliso

Prostaglandins Chemical imveliso 99% ubumsulwa API Material Lumigan Bimatoprost CAS 155206-00-1 ukunyanga iliso

inkcazelo emfutshane:


  • Ubuninzi:1.1 ± 0.1 g/cm3
  • Indawo yokubilisa:629.8 ± 55.0 ° C AT 760 mmHg
  • Indawo yokunyibilika:66-68 ° C
  • Imolekyuli:C25H37NO4
  • Ubunzima bemolekyuli:415.566
  • Indawo yokuflasha:334.7 ± 31.5 ° C
  • Umgangatho ochanekileyo:415.272247
  • PSA:89.79000
  • Ilog:1.98
  • Imbonakalo:ICrystal Solid, umgubo
  • Uxinzelelo lomphunga:0.0 ± 1.9 mmHg AT 25 ° C
  • Isalathiso seRefractive:1.591
  • Iinkcukacha zeMveliso

    Iithegi zeMveliso

    Qhagamshelana nam:

    Email:ceo66@hbainuodi.com

    Whatsap:+8618849057872

    Wickr: alice868

    Ukusetyenziswa

    I-Bimatoprost lichiza le-prostaglandin elaqala ukusetyenziswa ukunyanga izifo zamehlo ezifana ne-glaucoma.Igama lechiza nguLumigan.Nangona kunjalo, ngexesha lonyango, isigulane safumanisa ngokungalindelekanga ukuba ububanzi, ubude kunye nokuxinana kwee-eyelashes zakhe kuye kwanda kakhulu.Emva koko, i-bimatoprost isetyenziswe kwizilingo zeklinikhi zobuhle be-eyelash.Umphumo wayo omkhulu ekukhuleni kunye nokuqina kwe-eyelashes ngokuthe ngqo kwakhokelela ekuqalisweni kweLattise yinkampani yokuvelisa iLumegen, i-Allergan.Ichiza laqaliswa ngoDisemba 2008. Ivunywe yi-US FDA, ibe yimveliso yobungcali yokwenza i-eyelashes ibe mnyama kunye nokujiya.

    NgoJulayi 2006, i-bimatoprost-timolol maleate i-compound eye drops eye yaphuhliswa yi-United States Allergan Co., Ltd. yavunywa ligunya le-pharmaceutical ye-EU yokunciphisa impendulo kwi-block blocker ye-β-receptor okanye i-prostaglandins.Uxinzelelo lwe-intraocular okanye uxinzelelo lwe-ocular kwizigulane ezine-glaucoma evulekileyo engaphenduli ngokwaneleyo kunyango lwe-analog.I-compound eye drops iqulethe i-0.0Chemicalbook3% bimatoprost kunye ne-0.5% ye-timolol maleate, kanye ngosuku, inokubonelela ngonyango olusebenzayo kakhulu lwe-intraocular control effect, kwaye umphumo ungcono kune-bimatoprost yodwa.Matoprost okanye timolol maleate.Ulingo lwezonyango luqinisekisile ukuba iyeza linokunyamezela okugqwesileyo, kubandakanywa nokunciphisa i-40% kwisiganeko se-ocular hyperemia xa kuthelekiswa ne-bimatoprost yodwa.
    Kunyango lwe-glaucoma, ingasetyenziselwa kulwelo lokukhula kwe-eyelash, ugxininiso ngu-0.03%.

    Bimatoprost CAS 155206-00-1

    Iinkcukacha

    Igama lemveliso Bimatoprost
    CAS 155206-00-1
    Ukuxinana 1.1 ± 0.1 g/cm3
    Indawo yokubilisa 629.8 ± 55.0 ° C AT 760 mmHg
    Indawo yokunyibilika 66-68 ° C
    Imolekyuli C25H37NO4
    Ubunzima bemolekyuli 415.566
    Indawo yokuflasha 334.7 ± 31.5 ° C
    Umgangatho ochanekileyo 415.272247
    PSA 89.79000
    Ilog 1.98
    Imbonakalo ICrystal Solid
    Uxinzelelo lomphunga 0.0 ± 1.9 mmHg AT 25 ° C
    Isalathiso sokuqhafaza 1.591
    Iimeko zokugcina 20 °C

    Ezinye zeBimatoprost CAS 155206-00-1 Uphando:

    I-Olaparib yayisebenza ngokuchasene ne-Brca1; ii-p53 zebele zesisu (50mg/kg inaliti ye-intraperitoneal ngosuku), kodwa ayizange ibe nempembelelo kwi-HR-i-Ecad esweleyo; i-p53 yebele yamathumba.I-Olaparib yayingenayo i-dose-liming toxicity kwiigundane ezine-tumor.I-Olaparib isetyenziselwe ukunyanga amathumba kunye nokuguqulwa kwe-BRCA, njengomhlaza we-ovarian, umhlaza webele, kunye nomhlaza we-prostate.Ukongeza, i-Olaparib ithintele iiseli ze-tumor ezinqongopheleyo ze-ATM ngokukhethayo, icebisa ukuba i-Olaparib ingasetyenziswa njengearhente enokubakho kunyango lwe-ATM-mutated lymphoid tumors.
    I-Olaparib yi-PARP inhibitor ekwasebenza ngokuchasene nokuguqulwa kwe-BRCA1 okanye i-BRCA2.I-Olaparib inempembelelo encinci kwi-tanky (polymer) i-enzyme-1, kwaye ixabiso le-IC50 likhulu kunoko.I-Olaparib kwi-concentration ye-30-100nM isebenza kwiiseli ze-SW620 ukuze ingasebenzi i-PARP-1.Imigca yeeseli ezinqongopheleyo ze-BRCA1 (i-MDA-MB-463 [1] kunye ne-HCC1937) i-hypersensitive kwi-Olaparib xa ithelekiswa ne-BRCA1- kunye ne-BRCA2-yaneleyo yemigca yeseli (Hs578T, MDA-MB-23, T47D) I-Olaparib inqanda i-PARP kunye nokulungiswa kwesiseko , okubangela uvakalelo olunamandla lweeseli ze-KB2P kwi-Olaparib.Isiphumo kukuguqulwa kwekhefu le-single-strand ukuya kwi-double-strand breaks ngexesha lokuphindaphinda kwe-DNA, ngaloo ndlela kusebenze indlela yokudibanisa exhomekeke kwi-BRCA2.
    I-Bimatoprost yi-synthetic prostamide F2α derivative, enokukhetha ukulinganisa umphumo we-prostamine eveliswa emzimbeni, ukwandisa izinga lokuveliswa kwe-humor, ukunciphisa ukuchasana kokuphuma kwe-humor, kunye nokwandisa i-trabecular network channel kunye ne-uveal sclera. ibe lichiza lendawo elichasene neglaucoma elinesiphumo esinamandla sokunciphisa uxinzelelo lwe-intraocular.Ilungele unyango lwe-open-angle glaucoma (POAG) okanye amehlo aphezulu angasebenziyo kunye namanye amachiza okunciphisa uxinzelelo lwe-intraocular.Uxinzelelo lwegazi (OHT) izigulane.

    Qaphela:

    Ukuba unomdla, nceda uqhagamshelane nathi ngokukhululekileyo, siya kuphendula ngexesha.Hope sinentsebenziswano.


    Bhala umyalezo wakho apha kwaye uwuthumele kuthi