Chemical API CAS 84485-00-7 HCL Sibutramine
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Ulwazi olusisiseko
SibutramineI-hydrochloride iyiyobisi yokulahlekelwa kwesisindo, okuyiyo ifom ye-hydrochloride ye-sibutramine.Isenzo sayo se-pharmacological sifana ngokupheleleyo ne-sibutramine, kodwa ukuzinza kwayo kunye ne-solubility kungcono kune-sibutramine.
I-Sibutramine hydrochloride yaqala ukusetyenziswa ukunyanga ukudakumba.Kwisicelo sayo seklinikhi, abantu bafumanisa ukuba umphumo wokunciphisa ubunzima wawunamandla kakhulu kunempembelelo yayo ye-antidepressant.
Ngakolunye uhlangothi, inokunciphisa indlala kwaye ilawule ngokufanelekileyo i-caloric intake ngokuthintela ukuphinda kuthathwe i-serotonin;
Ngakolunye uhlangothi, inokunyusa ukusetyenziswa kwezicubu ze-adipose, ukuphucula imetabolism kunye nokukhuthaza ukusetyenziswa kwamandla ngokuvula i-adrenergic receptors;
Inomphumela ocacileyo wokulahleka kwesisindo, kodwa inokubangela iziphumo ezibi ezinje ngokunyuka koxinzelelo lwegazi, ukwanda kwesantya sentliziyo, i-anorexia, ukuphuthelwa, ukusebenza kwesibindi esingaqhelekanga, njl.
Sebenzisa: njenge-antidepressant
Ukusetyenziswa
Sibutraminei-hydrochloride, i-5-hydroxytryptamine kunye ne-norepinephrine reuptake inhibitor, ineempembelelo ezimbini zokuthintela ukutya kunye nokuphucula imetabolism, kwaye isetyenziselwa unyango lokukhuluphala okungenakulawulwa ngokutya kunye nokuzivocavoca.
I-Sibutramine hydrochloride inezichaso ezininzi zeklinikhi, ezifana noxinzelelo lwegazi olunzima, isibindi esinzima kunye nokungasebenzi kakuhle kwezintso.
1. Unyango lokukhuluphala kufuneka lusekelwe kulawulo lokutya kunye nokuzivocavoca.
2. Ukutyeba okubangelwa yi-Cushing's syndrome kunye ne-hypothyroidism kufuneka ingabandakanywa kububanzi bokusetyenziswa kwale mveliso.
3. Izigulane ezinembali yoxinzelelo lwegazi kufuneka ziyisebenzise ngononophelo.
4. Izigulane ezine-gallstones kufuneka zisebenzise le mveliso ngokuqaphela kuba inokunyusa okanye ikhulise ukubunjwa kwe-gallstones.
5. Le mveliso inokubangela ukuhlanjululwa komfundi, kwaye kufuneka isetyenziswe ngokucophelela kwizigulane ezine-glaucoma yokuvalwa kwe-angle.
6. Abaguli abakhe baxhuzula bafanele bayisebenzise ngononophelo, yaye abanesifo sokuwa bafanele bayeke ukuyisebenzisa.
7. Inokuchaphazela isigwebo, ukucinga okanye izakhono zemoto.